- Signaling Pathways
- GPCR/G Protein
- Oxytocin Receptor
Oxytocin Receptor
OXTR
The oxytocin receptor belongs to the G-protein-coupled seven-transmembrane receptor superfamily. Its main physiological role is regulating the contraction of uterine smooth muscle at parturition and the ejection of milk from the lactating breast. The oxytocin receptors are activated in response to binding oxytocin and a similar nonapeptide, vasopressin. Oxytocin receptor triggers Gi or Gq protein-mediated signaling cascades leading to the regulation of a variety of neuroendocrine and cognitive functions.
Oxytocin is a nonapeptide of the neurohypophyseal protein family that binds specifically to the oxytocin receptor to produce a multitude of central and peripheral physiological responses. In vivo, oxytocin acts as a paracrine and/or autocrine mediator of multiple biological effects. These effects are exerted primarily through interactions with G-protein-coupled oxytocin/vasopressin receptors, which, via Gq and Gi, stimulate phospholipase C-mediated hydrolysis of phosphoinositides.
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Oxytocin Receptor Related Products (84)
Related Products (84)
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Antibodies (2)
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L-365209
0 ImagesCat. No.: HY-120585CAS No.: 122211-30-7L-365209 is a oxytocin antagonist and can be isolated from Streptomyces . -
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Atosiban acetate (Standard)
0 ImagesCat. No.: HY-17572ARCAS No.: 914453-95-5Synonyms: RW22164 acetate (Standard); RWJ22164 acetate (Standard)Atosiban (acetate) (Standard) is the analytical standard of Atosiban (acetate). This product is intended for research and analytical applications. Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research. -
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OXTR modulator-1
0 ImagesCat. No.: HY-180870CAS No.: 415962-62-8OXTR modulator-1 is a OXTR modulator. -
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OXTR modulator-2
0 ImagesCat. No.: HY-180870ACAS No.: 415963-95-0OXTR modulator-2 is a OXTR modulator. -
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